What is onchocerciasis? How can you diagnose and treat this disease? Is ivermectin effective against onchocercia? And how much do you need to take? We cover the basics in this article. And in part two, we’ll discuss how ivermectin works against the parasite.
What is onchocerciasis?
Onchocerciasis is a common skin disease that spreads fast. It is a major health risk for those who live in remote areas near rivers. In some cases, it can even cause vision loss in its victims. It is mostly transmit through black fly bites. It affects more than fifteen million people worldwide, with approximately 1% living outside of Africa.
Onchocerciasis is a serious health condition that can cause temporary or permanent blindness. The disease manifests itself as patches of discolour skin, itching, and redness around the eyes. In severe cases, the disease can affect the cornea and lead to sclerosis. Eventually, the patient may suffer from night blindness and blurring vision.
diagnosis of onchocerciasis
Diagnosis of onchocerciases in humans requires an accurate and inexpensive test. The parasite’s DNA can be detect through a blood test or skin snip. Both procedures can be painful and transmit bloodborne infections. However, an alternative test is available that is not painful and does not require a skin snip. It uses a polymerase chain reaction (PCR) to detect the parasite’s DNA in samples taken from superficial skin scrapings.
To develop effective diagnostic tests, we have reviewed the literature on parasite detection in humans. This research reveals the importance of accurate parasite detection in the diagnosis of onchocerciasis. Microscopy is the gold standard for diagnosing the disease, but the sensitivity of microscopy is diminished if the infection is not severe.
Is ivermectin tablet effective against onchocercia
Ivermectin is a powerful drug that has been proven effective in the control of human onchocerciasis in many epidemiological settings. It works by inhibiting the growth of Onchocerca volvulus, the parasite that causes this disease. Its effectiveness has been demonstrat in several epidemiological settings, and the Merck Company has donate ivermectin for regional control programs in Africa.
The drug was discovere in 1974 by scientists at Merck Laboratories. It was later name “ivermectin” and marketed in 1981. It was not until a few years later that its effectiveness was confirm in human disease. Ivermectin was initially provided free of charge, and it is now available commercially under the name Mectizan.
dosage of ivermectin for onchocerciasis
Ivermectin dosage for onchocerciasis in humans varies depending on the parasite and the severity of the infection. Generally, patients should receive a single, 150-mcg dose daily. In severe cases, the drug may also be use in combination with antihistamines, antibacterials, or anti-inflammatory agents. In case of severe infections, patients may suffer from encephalopathy. To prevent severe complications, patients should be evaluate before receiving any ivermectin therapy.
Ivermectin is a highly effective treatment for onchocerciasis. Ivermectin for human has been shown to reduce the burden of onchocercal blindness and skin disease. It is safe and easy to administer. Ivermectin is now widely use in onchocerciasis-endemic communities.